Synthesis, Characterize and Antimicrobial Study of New Chalcones and Pyrazole Derivatives from Progesterone
Journal: International Journal of Science and Research (IJSR) (Vol.5, No. 3)Publication Date: 2016-03-05
Authors : Nisreen Kais Abood; Hiba Hayder Ibraheem;
Page : 833-836
Keywords : Progesterone; Chalcone; Pyrazole; Antimicrobial; Biological activity;
Abstract
The aim of this work synthesized a new series of chalcones and pyrazole derivatives from the progesterone, the new steroidal synthesized by the claisen-Schmidt condensation reaction, were react progesterone with different aromatic substituted aldehyde in presence sodium hydroxide afforded chalcones derivatives (1-6). Cyclized the chalcone derivatives by reaction with hydrazine hydrate to afforded pyrazole derivatives (7-12). All synthesized compounds were characterized by measurement melting point, FT-IR spectral, Elemental Analysis and some of them by 1H-NMR spectral and Antimicrobials activities.
Other Latest Articles
- An Efficient Way to Prevent Dos/DDos Attack in the Cloud Environment
- Ethno-Therapeutic Remedies for Women's Problems, in Dang District of Gujarat, India
- Characterization of Brain Glioma in MRI using Image Texture Analysis Techniques
- Identification the Presence of Vibrio Species by TCBS Media in Different Water Samples Collected from Different Locations
- A Review on Effective Algorithm to Secure Network Coding Systems against Wormhole Attack
Last modified: 2021-07-01 14:32:41