Study of a High-risk Group of Stage 2 Colon Cancer

AIM Adjuvant therapy is not routinely recommended in stage II colon cancer, but may be considered for high-risk patients. Our aim is to identify clinicopathologic characteristics in colon cancer stage II, which are associated with an increased risk of tumour recurrence and tumour-related death. OBJECTIVE AND METHODS For evaluating recurrence factors in Stage II colon adenocarcinoma, a clinical, non-experimental, longitudinal and retrospective study was done in the Department of surgery in Krishna hospital, karad from june2005 to june 2015. RESULTS In 200 eligible patients 20 (10 %) recurrence cases were observed that appeared in an average 2.3 years after surgery. The main site of recurrence was local-regional (5.5 %), pulmonary (2.5 %), hepatic (1 %), and peritoneal (1 %). The following factors were considered age, sex, CEA level, type of operation (elective or emergency), site of the primary injury, invasion (T3 or T4), lymphatic vessel invasion, histologic differentiation, and synchronous carcinoma. We found that patients more than 70 years old (p=0.0305) have a lesser disease-free time. Be more than 70 years old was the only recurrencerelated factor, this group has 2.56 times more risk of recurrence. No other studied variable was related to recurrence.