Correlation of Yolk Sac Diameter on TVS with Fetal Outcome

Objective To investigate the role of yolk sac diameter in between 9-10 weeks of gestation by TVS in prediction of pregnancy in an unselected population. Design Prostective observational clinical study of 100 cases. Setting Hindustan Aeronautics Ltd Hospital, Bangalore, Karnataka Material & method The study of 100 singleton pregnancies has been conducted at HAL hospital, Bangalore. Women attending routine ANC clinics were offered an early TVS of 3.4-5 MHz transducer between 9-10 weeks of gestation. Results 100 patients were screened for yolk sac diameter by subjecting them to TVS at 9-10 weeks at HAL hospital, Bangalore & followed up till delivery. All the 73 cases with yolk sac diameter 2-6mm had successful pregnancy outcome. Cases out of 22 cases with yolk sac diameter greater than6mm, 19 had missed abortion leaving 100 % sensitivity of abnormal yolk sac diameter with poor pregnancy outcome and a p value of significant 6mm is a good predictor of poor pregnancy outcome with sensitivity 100 %, specificity 96.3 %, PPV 86.36 %, NPV 100 %, accuracy 97 %.