Clinical Characteristics in Combined Pulmonary Fibrosis and Emphysema Syndrome vs Idiopathic Pulmonary Fibrosis Patients

Aim To identify differences between combined pulmonary fibrosis and emphysema syndrome (CPFE) and idiopathic pulmonary fibrosis (IPF) by a retrospective comparison of clinical data including clinical characteristics and baseline changes in pulmonary function. Methods We studied demographic, clinical and physiologic features for two groups of patients, (total N=26) those with CPFE (7 males and 5 females) and them with IPF (5 males and 9 females). Results The mean age was nearly the same. Predominates males smokers in CPFE. IPF patients had lower FVC and MRC values and higher PO2 values. Conclusions CPFE syndrome is a distinct entity. These patient are severely ill and should be differentiate from them with IPF.