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Novel Synthesis of Tetrazolopyrrolopyrimidines as Antifungal Agents
Journal: International Journal of Science and Research (IJSR) (Vol.5, No. 8)Publication Date: 2016-08-05
Authors : Shah Rina; Shah Nirmal M; Ramani Vivek;
Page : 207-209
Keywords : Tetrazolopyrrolopyrimidines; pyrrolo2; 3-dpyrimidines; diazotization; antifungal agents;
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Abstract
Synthesis of Tetrazolopyrrolopyrimidines 7, 9-disubstituted 7H-pyrrolo [4, 3-e]tetrazolo [1, 5-c]pyrimidines 2 of biological and synthetic interests has been conducted via novel route from 5, 7-disubstituted 3-amino-4-iminopyrrolo [2, 3-d]pyrimidines 1 by diazotization using sodium nitrite in acetic acid as nitrogen donor moiety.
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