Approach to Impaired Liver Function Tests

Initially, it is important to make distinction between liver function and liver enzyme which include, serum aminotransferases level and alkaline phosphatase level. Their elevations indicate hepatocyte and bile duct epithelial injury. However, albumin, bilirubin and prothrombin time are measures of hepatic function. But, these are affected by extrahepatic factors such as nutrition, hemolysis and antibiotic use.