The Effect of Extract of Senggugu to Mucociliary Transport, Nasal Sitogram and Quality of Life Inchronic Rhinosinusitis Patients

Introduction Extract of Senggugus root used during the rinse as one of the traditional medicine, has been widely used by Indonesian to clarifying voice and curing various respiratory disorders by entering the extract of senggugus root into the nose. The content extract of senggugus root, saponins and tannins has an effect on the function of cilia, nasal sitogram and quality of life chronic rhinosinusitis patients. Materials and methods A clinical open trial was performed in 20 patients with chronic rhinosinusitis, 10 patients with ekstract of senggugus root with the standard therapy and 10 of standard therapy patients only. Examination of mucociliary transport, nasal sitogram and quality of life conducted four times, before treatment, the second days, the sixth days and the tenth days after treatment. Data were analyzed with t-paired test and Wilcoxon test. Results This study shows the comparison of the value of neutrophils before and after the rotheca serrata extract of root water therapy + standard therapy, obtained significant value changes occurred in the treatment of rotheca serrata extract of root water therapy + standard therapy in all comparisons (p 0.05). Conclusion It shows that the provision of extract of sengugus root therapy to mucociliary transport will improve the nasal sitogram and the quality life of patients with chronic rhinosinusitis compared with the standard therapy only.