Efficacy Study of Asthmatic Disease using Single Human Hair Fiber ? A Spectroscopic Approach

Passing from normal tissue to pathological tissue, cellular biochemistry changes. From a diagnostic and therapeutic point of view, it is fundamental to study the physical and chemical changes occurring in the tissues and cells due to diseases and disorders. During the recent times the use of Fourier Transform Infrared spectroscopy (FTIR) has received quite a lot of attention not only for understanding the biological nature of the disease, but also for diagnosing it. In this study, it has been demonstrated that the study of FTIR-ATR spectra of single human hair fiber is used to differentiate between the healthy and asthmatic individuals. Significant differences are observed in terms of optical density of the absorption bands and a satisfactory analysis has been made using paired t test [1].