Cytochemical Study of Acute Leukemia in Special Relation to Children

Objectives study of childhood leukemia among the Hospital attending Patients in Gauahati Medical Colleges and Hospital. Material and Method The study was conducted in Gauhati Medical College and Hospital, Guwahati, Hospital in General Medicine Deptt. , Deptt. of Hematology from March (2002-Feb 2003). (as per Medical Registration Deptt. ) As per record 2002 total Hospital attending cases was 2, 65, 972 nos. where Indoor admission was 41, 448. Some of the Lab. works was done in the Deptt. Of Pathology Hospital Laboratory as well as College Hematology Lab. Total 70 No. of OPD patients were found with various groups of leukemia with various age groups. Patients were all age groups. Among them 50 was Male candidate where other 20 was females of different age groups. Out of 38 no. of were children and mostly 1st and 2nd decade of life (from 8 months to 13 yrs). Who were admitted in GMCH in the Department of Pediatrics, Hematology wards and General Medicine for Males and female wards respectively. Results Total 70 no. of different types of leukemia admitted into the hospital within a period of 12 months were studied for hematological finding and cytochemical reactions were analyzed. All available and relevant literature on hematological finding on leukemia was reviewed. Cases were analyzed and studied according to Hayhoe et al 1964, Cawley and Hayhoe 1972. Acute leukemia was observed 46 % while chronic leukemia was 24 % respectively. Conclusion Hematological cytochemistry should be routinely used as a reliable diagnostics aid for detection as well as classification and prognosis of different type of childhood leukemia.