Diabetes Mellitus and the Following Risk Factors Associated with an Increased Risk of COVID-19 Severity and Mortality in Adult Patients

Diabetes mellitus is one of the most common comorbidities in patients with COVID-19 and is associated with poor outcomes. This study aimed to investigate the association of diabetes mellitus with other risk factors in the severity and mortality of COVID-19 patients.Method: This retrospective study identified adult patients with COVID-19 admitted to Bali Jimbaran Hospital (Indonesia) from July 02, 2020, to May 04, 2021. The risk of severity and mortality were compared between COVID-19 patients with diabetes and without any comorbidities who were of the same sex and age. The other risk factors were explored in subgroup of patients with diabetes using logistic regression analysis.Results:The diabetes group had a significantly increased risk of COVID-19 severity (p less than0.001) and mortality (p =0.026). The logistic regression analysis showed that significantly increase COVID-19 patients? severity and mortality in diabetic patients with hypertension and D-dimer ?1000 ng/mL (p less than 0.05). Conclusions: Risk of COVID-19 severity and mortality generally increases in diabetes patients. Presence of hypertension or D-dimer ?1000 ng/mL were independent risk factor for both severity and mortality in COVID-19 patients with diabetes. Diabetes mellitus patients presenting with other risk factors must be take an extra attention to prevent a poor outcome.