Comparison of Anthropometric Profile and Heart Rate Variability Parameters between Women with Polycystic Ovarian Disease and Apparently Healthy Women

Background: Polycystic ovary syndrome (PCOS) patients reflect features like increased insulin resistance and adiposity, which can be results as autonomic dysfunction. Objective: To compare heart rate variability (HRV) between women with polycystic ovarian syndrome (PCOS) and apparently healthy women. To study the anthropometric profile of PCOS patients. Methods: 30 women with PCOS aged 20 to 40 years (as per Rotterdam criteria) were enrolled as cases and 30 age-matched women having normal ovulatory cycles were enrolled as controls. HRV was recorded. The following frequency-domain parameters were assessed: Low Frequency (LF), LF nu, HF nu, LF/HF ratio. Results: Mean BMI of PCOS women was 25.39?2.69 kg/m2. A total of 18 (60%) had BMI greater than25 kg/m2. Cases had significantly higher BMI, blood pressure as compared to control. Majority of cases (66.7%) had SBP/DBP greater than130/85 mmHg as compared to only 6 (20%) of controls (pless than0.001). For different frequency domain parameters, mean LF%, LF(nu) and LF/HF were significantly higher in cases as compared to controls. For all the other mean value was significantly lower in cases as compared to that of controls (pless than0.05) Conclusions: This study indicated that autonomic nervous system is affected by PCOS status of women.