Study of Endometrial Pathology in Abnormal Uterine Bleeding - A Retrospective Study

ABSTRACT INTRODUCTION:- Abnormal uterine bleeding (AUB) is the commonest presenting symptom and major gynaecological problem responsible for as many as one-third of all out patient gynaecologic visits. AIMS & OBJECTIVES:- The aim of study is to evaluate AUB in different age groups and carry out histomorphological study of the endometrium. MATERIAL AND METHODS:- The study was conducted on 303 patients in the department of pathology, SGT Medical and Hospital, Gurugram. Patients with isolated endometrial causes of abnormal uterine bleeding were included.Endometrial samples were obtained from dilatation and curettage or endometrial biopsy. Specimens were received in 10% formalin.These were studied grossly and were processed in automated tissue processor. Sections were stained with H and E. RESULTS:- The most common age group presenting with AUB was 31-40 years(36.96%). The commonest pattern in these patients was secretory endometrium 118 cases (38.94%) and proliferative endometrium 87 cases (28.71%). The commonest pathology was endometrial hyperplasia 38 cases(12.54%). Hormonal changes were seen in 3.30% cases and endometrial carcinoma in 0.99%. CONCLUSION:- Histological examination of the endometrium showed a widespectrum of pathological changes ranging from normal endometrium to malignancy thus emphasizing the importance of endometrial sampling as a diagnostic tool in the management of AUB