Dermatitis Herpetiformis with Celliac Disease: A Case Report

Background: Dermatitis herpetiformis (DH) is an autoimmune disease characterized by the existence of an extremely itchy papulovesicular eruptions. The prevalence of dermatitis herpetiformis is more common in Europeans and rarely in Asians, only 10-39 per 100,000 people population. Dermatitis herpetiformis events are most commonly associated with gluten-sensitive enteropathy or thecelliac disease. Case report: There is a reported case of dermatitis herpetiformis in a 42year old male. This patient complained of the appearance of blistersfilled with clear fluid that felt very itchy and increased in number on both arms, body, back, buttocks and legs since the past 2 weeks. In the dermatologic state, there were grouped of vesicles, bullae, hyperpigmented plaque, hyperpigmentation macule, erosion, excocriation of both upper and lower arms, body, back, both buttocks and both legs. The results of histopathological examination concluded the formation of dermatitis herpetiformis with the discovery of subepidermal multilocular bullae containing PMN leukocytes and PMN leukocyte cells (Papillary microabses) in the papillae dermis. Currently the patient is givendapsone 1x100 mg,cetirizin tablet 1x10 mg. The prescribed diet management is a gluten-free diet. Discussion: Dermatitis herpetiformis is associated with intolerance to gluten. Skin biopsy and immunofluorescence are the gold standard in this case. Gluten-free diet management and dapsone prescription are the main options in the treatment of DH.