Effect of Submucosal Application of Tramadol on Postoperative Pain after Single Dental Implant Placement: A Randomised Double-Blind Controlled Trial

This study aimed to evaluate the effectiveness of the submucosal application of tramadol, for acute postoperative facial pain, following the single implant placement in the mandibular posterior region. This prospective, double-blind, randomized placebo-controlled study included 40 ASA I-II patients undergoing single mandibular implant placement under local anaesthesia. Following the surgical procedure, patients were randomly divided into two groups; Group T (1 mg/kg in 2ml tramadol) and Group S (2-mL saline). Treatments were applied submucosally after surgery at implant site. Pain after implant placement was evaluated using a visual analog scale (VAS) 1, 2, 4, 6, 12, 24, and 48 h postoperatively. The time at which the first analgesic drug was taken, the total analgesic dose used, and adverse tissue reactions were also evaluated. In group T, postoperative VAS scores were significantly lower compared to that in group S (p less than 0.05). This study demonstrated that post-operative submucosal application of tramadol is an effective method for reducing acute post-operative facial pain after implant placement surgery.