PRODUCTION OF ANTINEOPLASTIC DRUGS FROM SOIL MICROORGANISMS
Journal: International Journal of Advanced Research (Vol.9, No. 5)Publication Date: 2021-20-05
Authors : C. Obula Reddy Deepika Damalla Divya Ganga; Divya Teja;
Page : 1228-1237
Keywords : Cancer Antineoplastic Drugs Streptomyces Cytotoxic;
Abstract
As number of cancer patients increasing, the number of chemotherapy treatments are also increasing. This analysis aims to provide a cutting-edge outline of the antineoplastic medications extracted from streptomyces. Streptomyces are the main source of antibiotic production. Antineoplastic medications moderate the pace of tumor development and postpone metastasis. The utilization and performance of the methods are discussed, with focus on the antineoplastic drugs. Streptomyces produces compounds and crude extracts which shows cytostatic reaction across different human cell lines like for breast carcinoma (MCF-7, MDA-MB-231 cell lines), (HepG2 cell lines) hepatic carcinoma, (DU 145 cell lines) prostate cancer and more.
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