DIAGNOSTIC UTILITY OF THE RAPID UREASE TEST FOR HELICOBACTER PYLORI IN GASTRIC JUICE SAMPLES

Objective: The purpose of this study is to compare the diagnostic performance of the rapid urease test for H. pylori in endoscopic samples of gastric juice compared with the same test in gastric mucosa. Materials and methods: Cross-sectional, comparative and prospective study with study of concordance of diagnostic tests, carried out with patients referred to a medical center in Bogotá DC, Colombia for the performance of an esophagogastroduodenoscopy. We included 130 patients older than 18 years, without antibiotic treatment or inhibitors of gastric secretion, or with any type of immunodeficiency, or cancer. Were processed in the sensibacterpyroli test device a sample of gastric antrum for Rapid Ureasa Test RUT in mucosa and for the sample of juice 5 mL was taken with suctionator 7A-23B pulmomed (USA) R, to compare results. Results: In this study the infection by Helicobacter pylori was detected by biopsy sample in 40.8% of the patients that corresponded to 53 patients, among (59.2%) 77 patients with negative values. The prevalence of H. pylori infection in this study was 40.8%. It was calculated of VPP and NPV: 95% and NPV: 89.3%. Conclusions: rapid urease test in gastric juice is a fast and economic test, with very good sensitivity and specificity, is also very useful to detect H. pylori infection.