Comparing the Inflammatory Markers between Women with Eclampsia- Preeclampsia and Normotensive Pregnant Women in Gynecology
Journal: Journal of Medicinal and Chemical Sciences (Vol.4, No. 6)Publication Date: 2021-11-01
Authors : Sarehnaz Aghili; Toktam Alirezaei; Shahin Nikmanzar; Soraya Salehgargari;
Page : 571-578
Keywords : Hypertension; preeclampsia; Eclampsia; pregnant mothers;
Abstract
Hypertension is a medical problem during pregnancy and one of the types of hypertensions during pregnancy is eclampsia-preeclampsia. The aim of this study was to compare inflammatory markers between women with eclampsia - preeclampsia and pregnant women with normal blood pressure admitted to the gynecology ward of Shahada Tarnish and Mehrieh hospitals in 1998-99. This descriptive-analytical study was performed with a cross-sectional design. The study population consisted of all patients diagnosed with eclampsia-preeclampsia and pregnant mothers in Shohada-e-Tajrish and Mahdieh Hospitals in Tehran during 2019 to 2020. The study sample consisted of 400 patients who were selected by convenience or convenience sampling method and 200 patients with a diagnosis of eclampsia-preeclampsia were in the experimental group and 200 pregnant women were in the control group. The subjects completed pre-prepared forms for study variables, i.e. information on maternal age, maternal weight, infant weight, gestational age, neutrophil count and lymphocytes. To analyze the collected data, tests such as Pearson correlation coefficient and independent t-test were used and analyzed by SPSS software version 23. The results showed that a statistically significant difference was found between NLR and PLR MPV. Finally, the results of this study showed that platelet count; MPV, NLR, PLR were significantly different in the two groups of preeclampsia patients and pregnant women with normal blood pressure and that these indicators can be used to predict preeclampsia.
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