Barrier Integrity Damage-Elicited Allergic Response (BIDEAR) Syndrome: A Proper Entity?

This brief report shows different cases of allergic sensitization elicited by mechanical trauma. The role of the accidental trigger is considered as part of a proper pathological entity, as long as the barrier damage in concert with the pro-allergic immune response was a key factor in the eliciting of the allergic carrier. In this context, we attempted to integrate the event of traumarelated barrier destruction as a constitutive part of a proper diagnostic entity when allergic sensitization is elicited as a result of the mentioned accident, suggesting the term: “Barrier Integrity Damage-Elicited Allergic Response (BIDEAR) Syndrome”.