The Effect of Grape Seed Extract Mouth Rinse on the Caries Activity, Dental plaque and Gingivitis

Objectives: This study aimed to evaluate the effect of mouth rinse containing grape seed extract (GSE)on caries activity, plaque accumulation and gingivitis. Material and Methods: A total of ninety-five healthy children participate in a clinical trial, they divided into two groups, group 1: grape seed extract mouth rinse (prepared for this study) (test group) and group 2: chlorhexidine mouth rinse (positive control group). The evaluation of caries activity, dental plaque accumulation and gingivitis were done prior to and on weekly basis for 3 weeks. The effect of mouth rinses was evaluated using one-way ANOVA test to compare baseline scores with different follow up scores. Multiple comparisons within each group were done using Post-hoc test. Comparison between the two groups was done using Un-paired t test. p values less than 0.05 were considered statistically significant. Results: The efficacy of GSE mouth rinse was comparable to that of chlorhexidine in reducing the dental caries activity, dental plaque accumulation and gingivitis.Conclusion: GSE mouth rinse may be used as a self-applied preventive measure to maintain healthy oral and dental tissues in the future.