Effectiveness Of Anti-Inflammatory Properties Of Combination Of Bromelain,Trypsin And Rutoside With Combination Of Diclofenac And Serratiopeptidase Following Surgical Removal Of Impacted Mandibular Third Molar- A Randomised Double Blinded Clinical Tria

The surgical removal of impacted mandibular third molars is one of the most performed Dento-alveolar procedures, associated with varying degrees of postoperative discomfort. Pharmacologic strategies for minimizing the clinical manifestations of surgical injury are therefore, logically directed at blocking the formation or inhibiting the effects of mediators of acute inflammation. NSAIDs are being used very extensively all over the world but their chronic use may lead to side effects such as gastric ulcers and liver kidney damage. Considering these facts, the use of drugs of natural origin with lesser hazards is a positive alternative. Bromelain, Rutoside and Trypsin are known to have a very promising role in relieving inflammation and promote wound healing.