Social Isolation as Risk Factor of Stroke: Protocol for Systematic Review

Introduction: The purpose of this study protocol is to provide the methodology of the review and to estimate the influence of social isolation on stroke incidence. The negative influence of psycho-social factors on the health of individuals has been discussed in several literatures 7–13 but the mechanism of social isolation on stroke occurrence has been not clearly explained in the previous studies as a very high risk factor to fear. It's that why is very important to plan this systematic review in view to have a good understanding about the relationship existing between isolation and stroke occurs to have a good follow-up of this disease. Methodology: A complete search of published studies will be conduct until May, 2021 using MEDLINE, Embase, PubMed, Science Direct and Springer. Prospective and retrospective studies to evaluate the influence of social isolation on stroke incidence. After eliminating copies, the eligible articles will be screened by researchers then extraction and evaluation of the quality data will be done independently. Any disputes will be solved by discussion or the arbitration of a third author. Ethics: Moral consent is not intended for the study, as we will only collect data from published available articles. This paper will be conducted to a peer journal for publication after completion.