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Acute Generalized Exanthematous Pustulosis in a Child without Drug Intake: Clinical and Histological Features

Journal: International Journal of Pediatric Health Care & Advancements (IJPA) (Vol.05, No. 05)

Publication Date:

Authors : ;

Page : 95-98

Keywords : Acute Generalized Exanthematous Pustulosis; Pustular Dermatosis; Generalized Pustular Psoriasis; NonFollicular Pustules; Histology.;

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Abstract

Acute generalized exanthematous Pustulosis (AGEP) is a rare and sometimes life-threatening, cutaneous reaction caused by drugs in more than 90% of cases, with antibiotics the most frequent triggers. It is a potentially fatal skin reaction rarely observed in children and can be atypical in its presentation. Clinically, it is characterized by the acute onset of dozens of sterile,non-follicular, small pustules on edematous erythema, few hours to three weeks after exposure to the causative agent. The lesions begin on the face and/or skin folds, with widespread distribution after. Systemic symptoms are mild and the disease normally resolves spontaneously after the inciting agent is withdrawn. We report a rare case of AGEP in an 8-year-old boy with no history of drug intake. Through our case, we highlight the atypical clinical and histological presentation, with special concern of the therapeutic options especially in children.

Last modified: 2021-12-08 22:02:48