A New Eruptive Fever Associated With Stomatitis And Ophthalmia

A Century-old story of Stevens Johnson Syndrome/Toxic Epidermal Necrolysis – Need for a paradigm shift in its management. Albert Stevens, a surgeon and Frank Johnson, a pediatrician, published a paper entitled “A New Eruptive Fever Associated with Stomatitis and Ophthalmia” in the American Journal of Diseases of Children in 1922 [1]. The paper described two young boys who presented with skin eruptions of oval, dark red to purplish spots separated by normal tissue associated with fever, conjunctivitis, inflamed mucous membrane. One boy had total loss of vision. This was the first description of a condition which was later known as Stevens-Johnson Syndrome (SJS/TEN).