Intestinal gangrene as the presenting manifestation of acute promyelocytic leukemia

Bleeding, often catastrophic, is common, however, thrombosis is rare in Acute Promyelocytic Leukemia (APL). Intestinal gangrene is an unusual presentation of thrombosis of mesenteric vasculature. We hereby, for the first time report this unusual presentation of intestinal gangrene secondary to leukaemic infiltration in APL and highlight the importance of prompt therapeutic intervention given its catastrophic nature.