Effect of Electric Cigarette Smoke Exposure on Spermatozoa quality of mice (Mus musculus L)

E-cigarette is one of the cigarettes that many used. E-cigarette smoke can cause disturbance in reproduction system. Chemical contents in e-cigarette smoke can increase free radicals that can cause oxidative stress. This purpose of this study to know the effect of e-cigarette smoke exposure to spermatozoa quality of mice (Mus musculus L). The tested animal were divides into 4 groups, every group consists of 6 mice that given treatment that is e-cigarette smoke exposure with a volume of L ml, 2 mL, and 4 mL for 4 weeks. Nicotine content in e-cigarette liquid was 6mg/mL. The parameter observed were percentage of motility and abnormal spermatozoa morphology. The conclusion of this study is e-cigarette smoke exposure decreased spermatozoa quality that is increased abnormal spermatozoa morphology in the treatment of e-cigarette liquid volume of 2 mL and 4 mL, meanwhile in spermatozoa motility is tend to decrease.