Oxidation Kinetics of some Amino Acids by 1-Chlorobenzimidazole in Acid Medium - A Kinetic and Mchanistic Approach

The major product, carboxylic acid, is also revealed in the product review. The oxidation kinetics mechanism proposed is consistent with observed kinetic data. The reactions were monitored potentiometrically up to 70% completion using a platinum-saturated calomel electrode assembly to track the potentials of the reaction mixture containing varying concentrations of the [CBI] / [BI] couple (BI = benzimidazole) at regular intervals. Using linear plots of log(Et – Eα) versus time, the pseudo-first-order rate constants,k1, were estimated (r0.999)The reactions were found to be first-order, each with respect to [amino acids] and [oxidant]. The rates of the reactions decreases with the added HClO4, and the order in [HClO4] was inverse fractional. The rate of reaction decreases as the dielectric constant of the solvent medium decreases, indicating a dipole-dipole reaction. Electrolytes, such as sodium perchlorate, have little effect on reaction rates. The addition of benzimidazole, one of the reaction ingredients, slowed down the reaction rates. When acrylonitrile was applied to the reaction mixture, no polymerization occurred. The thermodynamic parameters were measured after the kinetic runs were carried out at four different temperatures. The results of the reaction were carboxylic acid, ammonia, and carbon dioxide, according to the report. The most likely reactive species have been identified as HOCl. The observed kinetic effects that have been derived are compatible with a fitting mechanism.