Chlorpromazine-HCl Determination via Its Oxidation with Sodium Nitrite in Sulfanilic Acid Medium via CFIA Technique through Long Distance Chasing Photometer NAG-ADF-300-2

In this work, precipitation reaction with a new photometer NAG-ADF-300-2 analyzer was used to detect chlorpromazine hydrochloride by attenuation of incident light (White Snow Light Emitting Diode) at two steps, the first 110 mm and the second 60 mm with a separation distance of 100 mm of the chlorpromazine-hydrochloride reaction with a mixture of two reagents of sodium nitrite and sulfanilic acid form a yellowish-white precipitate. The attenuation of this precipitate by incident light was measured in a highly repeatable and reproducible way from a relative standard deviation percent (RSD %) of less than 0.3% at a variable concentration. The linear dynamic graph ranges from 0.5 to 45 mmol.L-1 for Cell A and 1-43 mmol.L-1 for Cell B, with a limit of detection (L.O.D) 0.9984 μg and 49.9239 μg at 281 μL sample, and a correlation coefficient (r) of 0.9994, 0.9993 for Cell A and Cell B, respectively