Comparison of ONH, GCC and RNFL with SDOCT in Normal, Pre-Perimetry and Glaucoma Patients

The purpose is to compare the ability of spectraldomain optical coherence tomography (SDOCT) retinal nerve fiber layer (RNFL), optic nervehead (ONH), and macular measurements (GCC) todetect glaucomatous damage. Methodology: This study was prospective, cross-sectional observational study.All patients went under the detailedglaucoma Workup.Patients were categorized in control group, pre-perimetry, Glaucoma with Normal visual field and Glaucoma with Visual field changes. Optic Nerve Head (ONH), RNFL parameters and Macular measurements (GCC) were tested by SDOCT. Results: Total 204 eyes of glaucoma patients were included with mean age M=57.55, SD=10.60. Oct ONH, Average RNFL and GCC analysis was done. Mean Average RNFL showed significant change between control (92.29?10.23) and glaucoma group(67.17?14.12)pless than0.05.Average GCC+IPL in control group (80.15?6.51) and glaucoma patients(62.74?13.52)pless than0.05. Diagnositic ability was tested in Average RNFL (0.80) and Average GCC (0.77) were found to be largest AUC curve. Conclusion: Our results have significant implications for the use of the SDOCT technology for diagnosing structural damage in eyes havingglaucoma.