Cytogenotoxic Effects of Carbaryl (Sevin) in Channa Punctatus in Vivo

Cytogenotoxic effect of the carbamate insecticide carbaryl (Seven?) to live fish Channa punctatus was studied. We analysed the induced sister chromatid exchanges (SCE) frequencies, chromosomal aberrations (CA), cellular proliferation rate in mitotically dividing cells of kidney and micronucle (MN) i in peripheral erythrocytes of Channa punctatus following in vivo exposure to three different concentrations of carbamate insecticide (Carbaryl). Our result revealed that the insecticide induced significantly high incidences of micronuclei in peripheral erythrocyte, chromosomal aberrations as well as sister chromatid exchanges, inhibited mitotic index and caused considerable delay in the generation time of kidney cells in treated organisms. The effects were found to be depend upon dose as well as period of exposure to the chemical. The experimental data showed carbaryl as cytogenotoxic to fish per se. These results have implications in the use of pesticides in the agricultural field.