Prevalence and Clinical Spectrum of Vitamin B-12 Deficiency

Introduction: Vitamin B12 is an important nutrient that the body uses to serve as a cofactor in many main cell reactions. Cobalamin, in combination with folate, is necessary for DNA synthesis in cells that undergo rapid turnover, such as haematopoietic and enteric lining cells. Increased homocysteine, reduced methionine, and impaired tetrahydrofolate formation are the physiological effects of either of the above nutrients deficiency. Material & Methods: Quantitative research approach will be adopted in current research study, Non experimental descriptive research design will be used in this study. Research study for this study was Neurological OPD and hospitalize patient in bansur hospital, Bansur. Sample size was 40 patient at Bansur Hospital OPD. Result: The results obtained were considered statistically significant at 5 percent level of significance (p ? 0.05). Data was presented in the form of tables, graphs and diagrams. Discussion: Present studies assess the prevalence and clinical spectrum of vitamin b-12 deficiency in a cohort of patient presenting with neurological disorders in tertiary care hospital of Rajasthan.