SOME IMMUNOLOGICAL PARAMETERS OF VIRAL PEDIATRIC PNEUMONIA

This study was planned to diagnosis of some viral causative agents addition to clinical signs and symptoms and study some immunological biomarkers for pediatric pneumonia. This work is clinically used diagnosed children patients (n =100 ) of pneumonia were chosen and in addition to (n = 40 ) apparently healthy children as a control group between October 2013 to July 2014. Specific diagnosis is clinically done by consultant physicians for all studied patients. The patients were distributed into three groups according to the age, <1 year (40) patient, 1-3 years (30) patient and 4-5 years (30) patient. The results of IIFA showed that the specific (IgM) antibody were detected in serum of infection patients. The viral causative agents of pneumonia diagnosed are 47%divided into single viral agents (37%) have five genera adenovirus(14%), parainfluenza (11%), respiratory syncytial virus(10%), influenza B(2%)and influenza A(0%) and mixedviral agents(10%) (viral with viral cause). Adenovirus with Respiratory Syncytial virus(6%), Adenovirus with Parainflunsa(4%), The WBCs count showed high significant increase at (P<0.05) of concentration in patient groups10.51±3.82cell/cu mm comparison with control8.17±1.83cell/cu mm, viral causes 10.93±3.75cell/cu mm and mixed causes 12.73±3.40cell/cu mm. A significant increase of neutrophil cells count patients 4.54±2.41 cell/cu mm comparison with control 3.87±1.045 viral causes 3.78±2.49 cell/cu mm and mixed causes 5.81±2.03 cell/cu mm. A high significant increase was shown in lymphocyte cells count of pneumonia patients 4.65±2.56 cell/cu mm when camper with control 3.33±0.834cell/cu mm was appeared in viral causes 5.58±1.88cell/cu mm and mixed causes 5.39±3.14cell/cu mm. A significant increase in patients CRP 9.72±13.24mg/l comparison with control 3.40±1.08mg/l appear in mixed causative agents groups12.17±17.08mg/l but not observe in viral causes7.22±11.16.