EVANS Syndrome - A Rare Cause of AIHA with ITP: A Case Report
Journal: International Journal of Science and Research (IJSR) (Vol.11, No. 1)Publication Date: 2022-01-05
Authors : Dr Shruti Bharat Nelekar; Dr M. A. Jamadar;
Page : 184-187
Keywords : AIHA; ITP; neutropenia; autoimmune disorder; corticosteroids; IVIG; Immunomodulators;
Abstract
Background: Evan's syndrome is a rare autoimmune hematological condition, characterized by warm antibody AIHA with ITP with or without neutropenia. Secondary associations may include connective tissue disorders, infections and malignancies. Introduction: We present a case of a middle aged female patient who presented with anemia, bleeding manifestations refractory to repeated transfusions. Clinical features and laboratory and immunological workup was done and diagnosis was Evan's syndrome was made. Interventions: blood transfusion initially given to alleviate symptoms and corticosteroids were started. Outcome: with corticosteroids patient experienced dramatic improvement and patient is being followed up monthly and no remission is observed with the steroid doses being tapered. Conclusion: It can be concluded that considering Evan's syndrome in the differential diagnosis of AIHA and ITP can help to initiate early treatment with steroids, IVIG or immunemodulators and prevent the dreadful complications of massive bleeding.
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Last modified: 2022-02-15 19:04:11