REDUCING POST OPERATIVE NAUSEA AND VOMITING (PONV) IN NEUROSURGICAL PROCEDURES: OUR TERTIARY CARE EXPERIENCE
Journal: International Journal of Advanced Research (Vol.10, No. 01)Publication Date: 2022-01-15
Authors : Aymen Masood Khan Azhar Ajaz Khan Anzeen Nazir Kanth Suhail Masood Khan; Owais;
Page : 768-773
Keywords : Neuro - Anesthesia Palonosetron Nausea Vomiting;
Abstract
Aim:Patients undergoing elective neurosurgical procedures were observed to determine the therapeutic efficacy of two different dosages of palonosetron. Materials and Methods:Patients undergoing elective neurosurgical procedures were randomly allocated to one of three groups: control (n = 30), 0.05 mg palonosetron (n = 30), or 0.075 mg palonosetron (n = 30). At the start of the dura mater closure, the medicines were administered intravenously. Anesthesia was maintained with 1 MAC sevoflurane in a 50/50 combination of air and oxygen. The patients were observed for 72 hours after extubation for postoperative nausea and vomiting. Results:The 0.075 mg palonosetron group had considerably less nausea than the control group in the first 6 hours (P = 0.019). At 0–72 hours after surgery, the incidences of nausea, retching, and vomiting in the 0.075 mg palonosetron group were considerably lower than in the 0.05 mg palonosetron or saline groups (P 0.001). Conclusion:PONV was decreased more efficiently in the 0.075 mg palonosetron group than in the 0.05 mg palonosetron and control groups in neurosurgicalpatients.
Other Latest Articles
- A PROSPECTIVE STUDY ON THE INCIDENCE AND RISK FACTORS OF WOUND DEHISCENCE OF EMERGENCY LAPAROTOMY SURGERIES IN A TERTIARY CARE HOSPITAL
- THE ROLE OF VITAMIN D IN PRE ECLAMPSIA AND ASSOCIATION OF ITS DEFICIENCY WITH SEVERITY OF PRE ECLAMPSIA
- CORNEAL TOPOGRAPHIC CHANGES AFTER PTERYGIUM EXCISION WITH CONJUNCTIVAL AUTOGRAFTING USING SUTURES VERSUS FIBRIN GLUE: A COMPARATIVE STUDY
- THE SIGNIFICANCE OF CERTIFIED SECURITY PROFESSIONAL (CSP) CERTIFICATION PROGRAM IN HARNESSING LEADERSHIP CAPABILITIES IN THE FIELD OF INDUSTRIAL SECURITY
- BASAL CELL CARCINOMA WITH LYMPH NODE METASTASIS A CASE REPORT AND REVIEW OF LITERATURE
Last modified: 2022-02-22 21:42:00