Biflavanoids from Semecarpus Anacardum L.f., Their Biological Aspects and Docking Studies
Journal: Journal of Pharmacy and Pharmacology (Vol.10, No. 1)Publication Date: 2022-01-01
Authors : Vustelamuri Padmavathi;
Page : 25-32
Keywords : Semecarpus anacardium L.f.; anacardiaceae family; biflavanoids antimicrobial activity; anticancer activity; antioxidant activity.;
Abstract
Biflavanoids has been isolated from the Semecarpus anacardium L.f Nuts, Leaves, Flowers, Stem bark and Root bark. These were characterized through chemical and spectral data, and also nutritionally considered them as a new non-conventional supply for pharmaceutical industries and edible purposes, knowledge concerning the composition and properties of Semecarpus anacardium L.f would assist in efforts industrial, nutritional and application of this plant. To explore the binding mode and understanding of key active site residues of the extracted natural compounds such as fatty acids in the active site, docking studies were carried out by taking the crystal structure of human FAAH (PDB ID: 3K84). Docking studies indicated the presence of 20 (Amino acids) amino acids in the active site. Phytocomponents in the extract imply the phytopharmaceutical importance of the plant. Most of the chemical compounds can target both gram-positive and gram-negative bacteria, anti canceractivity; radical scavenging activity is being reported for the first time.
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