TREATMENT OF EXTREMELY PREMATURE NEWBORN INFANT WITH INO. CLINICAL CASE
Journal: International Education and Research Journal (Vol.5, No. 11)Publication Date: 2019-11-15
Authors : Radulova P. Slancheva B. Marinov R.;
Page : 30-34
Keywords : bronchopulmonary dysplasia; pulmonary hypertension; extremely premature infant; inhaled nitric oxide;
Abstract
Prolonged inhaled nitric oxide (iNO) from birth in preterm neonates with BPD improves endogenous surfactant function as well as lung growth, angiogenesis, and alveologenesis. As a result there is a reduction in the frequency of the “new” form of BPD in neonates under 28 weeks of gestation and birth weight under 1000 gr. Delivery of inhaled nitric oxide is a new method of prevention of chronic lung disease. According to a large number of randomized trials iNO in premature neonates reduces pulmonary morbidity and leads to a reduction of the mortality in this population of patients. This new therapy does not have serious side effects. We represent a clinical case of extremely premature newborn infant with BPD treated with iNO.
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