INO IN PREMATURE NEWBORNS – SHORT AND LONG TERM OUTCOME

According to a rising number of randomized controlled clinical trials the “off label” usage of iNO in premature babies is rising in the last few years. Nowadays in the era of the precise medicine it is of great importance to differentiate the population of premature babies with critical hypoxic pulmonary failure that is most likely to gain positive effect from iNO treatment. The described trial compares the iNO therapy with the conventional therapy regarding the short and long term outcome in premature newborns below 30 week of gestation. A group of premature infants with specific characteristics is clearly defined, where the usage of iNO leads to positive effect concerning the outcome.