Repeated administration of autogenous vaccine decreases papillomatosis in female bovines

Objective. Theaimof the present study was to evaluate the control of bovine papillomatosis (BP) with an autogenous vaccine under tropical conditions in the State of Guerrero, Mexico. Materials and methods. For the experiment, 18 cows were used, divided in three treatment groups according to the ranch (six cows per group). Treatment 1 (T1-immunevaccine), treatment 2 (T2-histovaccine) and treatment 3 (T3-plasma therapy). Results. At the beginning of the study, a high incidence of papillomas was encountered among cows [(T1 (190 papilloma), T2 (95 papilloma) and T3 (100 papilloma)]. The administration of the autogenous vaccine produced a significant reduction (T1 and T3) in the papillomas number through the applications from 1 (147 and 66 papillomas) to 5 (10 and 9 papillomas); (p<0.05). There was also a significant difference among treatments according to the period of application (3 to 5) decreasing the number of lesions (period effect; p<0.05). In addition, an interaction treatment x period was observed, decreasing the number of papillomas in the fourth and fifth administrations (T1 and T3; p<0.05). Conclusions. The repeated administration of the autogenous vaccine in female bovines decreased the number of papillomas at the fourth and fifth application in treatments 1 and 3.