A SHORT-TERM REVIEW ON SOLID LIPID NANOPARTICLES
Journal: International Journal of Pharmaceutical Sciences and Medicine (IJPSM) (Vol.7, No. 5)Publication Date: 2022-05-30
Authors : MOHANRAJ.S; JAYANTHI.B;
Page : 1-17
Keywords : Solid Lipid Nanoparticles; Characterization; Colloidal Dispersions; Preparation Methods and Applications;
Abstract
In recent years, Solid lipid nanoparticles (SLNs) have been given a lot of attention as a potential drug distribution alternative to existing colloidal dispersion technologies. The use of SLNs as a pharmaceutical carrier has gotten a lot of focus in recent years. Nanostructure lipid carriers and SLNs are non-toxic since they are biodegradable. SLNs have various distinct properties in terms of therapeutic uses. SLNs are lipid-based nanocarriers with sizes ranging between 10 to 1000 nanometers. Decomposition of the drug can be protected by the drug entrapped in a lipid, physical stability; controlled drug release and remarkable acceptability are all benefits of SLNs over traditional drug carriers. The capacity to incorporate pharmaceuticals into nanocarriers opens up a new paradigm in drug delivery that could hold enormous promise in terms of improving bioavailability while also allowing for controlled and sitespecific drug delivery. This article covers the manufacture and characterization of SLNs, as well as the administration and medicinal uses.
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Last modified: 2022-05-19 18:26:48