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SERUM MAGNESIUM LEVEL IN TYPE2 DIABETES MELLITUS WITH SPECIAL REFERENCE TO DIABETIC RETINOPATHY

Journal: International Journal of Advanced Research (Vol.10, No. 04)

Publication Date:

Authors : ; ;

Page : 623-627

Keywords : Diabetes Mellitus Diabetic Retinopathy Magnesium;

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Abstract

Background: Diabetes mellitus (DM) is a worldwide, growing epidemic, with an estimated 415 million adults globally. Patients with diabetes are at increased risk of death and a triad of serious diabetes-specific complications (neuropathy, nephropathy, and retinopathy) and other associated complications. Magnesium is an intracellular cation and co-enzyme for various reactions of glycolytic pathway. Hence, we evaluated serum magnesium level in type 2 DM with and without diabetic retinopathy. Materials and methods: The study is carried out on 40 patients of type 2 DM with retinopathy and 40 patients of type 2 DM without retinopathy. All patients are subjected to the detailed history taking, ocular examination, and investigations like serum magnesium, FBS, PPBS, glycated hemoglobin. Results: The study revealed that there is a significant decrease in serum magnesium level in diabetic patients with retinopathy than without retinopathy (t= -6.297, df= 58 p= <0.001).Similarly Fasting Blood sugar, post prandial blood sugar and duration of diabetes also show significant difference. Conclusion: As magnesium level decreases in patients with type 2 DM, the prevalence of retinopathy increases. Timely monitoring of serum magnesium levels and glycated hemoglobin as well as appropriate interventions would be beneficial in early detection and treatment of diabetic retinopathy.

Last modified: 2022-05-25 16:26:46