Study on chloramphenicol resistance pattern in Central India, Indore

Background Chloramphenicol (CK) is a drug of choice in many life threatening and serious bacterial infections. Due to the development of resistance and toxicity associated with this drug, it is not in common use now days. This study was done to fi nd out the prevalence of CK resistance pattern. Materials and Methods A total of 100 consecutive pus samples from the surgical site infections from various specialties of index medical college hospital and research center were studied in the microbiology department during the period of 1 year. Results Gram-positive as well as Gramnegative organisms had shown sensitivity to Chloramphenicol. Furthermore, organisms were resistant to commonly used higher antibiotics. Conclusion CK can be used for common serious ICU patients not having contraindication to this drug. Study also reinforces proper and rational use of antibiotics.