Use of recombinant interleukin-2 in traumatic disease in veterinary medicine
Journal: RUDN Journal of Agronomy and Animal Industries (Vol.17, No. 2)Publication Date: 2022-06-19
Authors : Oksana Gizinger;
Page : 210-220
Keywords : veterinary medicine; immunity; correction of immune disorders; animals; cytokines; interleukin-2; Roncoleukinum; traumatic disease;
Abstract
Тhe article presents analysis of current information on the possibility of using recombinant interleukin-2 in traumatic disease in veterinary medicine. The analysis included publications from the following databases - P ubMed, MedLine, BIOSIS, ToxiNet, CANCERLIT, CINAHL, CISCOM, EMBASE, International Pharmaceutical Abstracts, and NAPRALERT, using 10 keywords and their combinations. It was shown that in trauma of any genesis, an immunodeficiency state occurs associated with an imbalance of Th1/Th2 cytokines. The use of recombinant interleukin-2 restores synthesis of endogenous interleukin-2, provides adequate targeted drug correction of immune dysfunctions, increasing the clinical and immunological effectiveness of therapeutic measures.
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Last modified: 2022-06-19 23:39:58