Spirometric Abnormalities Met among Senegalese Workers Exposed to Chlorine Gas
Journal: Journal of Pharmacy and Pharmacology (Vol.7, No. 11)Publication Date: 2019-11-11
Authors : Houndjo Salimata Diagne; Ouattara Rokia; Mbengue Arame; Ouedraogo Valentin; Seck Aissatou; Sow Abdou khadre Diaw Mor Toure Maimouna; Coly Mame Saloum; Ba Awa; Sar Fatou Bintou; Ba Abdoulaye; Samb Abdoulaye;
Page : 584-592
Keywords : ;
Abstract
Introduction: Chlorine as a disinfectant has many side effects on respiratory function. This respiratory toxicity may be related to the exposure time. Materials and Methods: Measure the impact of the duration of chlorine gas exposure on the respiratory function of Senegalese workers who work in the national water production factory: Senegalaise Des Eaux (SDE), aged 35-54 years. Twenty-four (24) male subjects exposed to chlorine gas were divided into two groups, one (35-44) and the other (45-54). Clinical examinations were performed on each employee, followed by chest x-rays and spirometry. We included all subjects whose first or last two spirometry results were normal. Results: In the 35-44 years group, 50% of subjects had disturbed spirometry including 41.6% of obstructive syndrome (OS), at the second spirometry and 8.3% had a restrictive syndrome FVC at -25%, at the 3rd spirometry 4/12 had a normal spirometry. The duration of exposure was 10 years. For subjects in 45-54 years, 8/12 had persistent OS or accentuated, then at the 3rd spirometry we had 10 subjects. The duration of exposure was 17.5 years. Conclusion: Compared with (35-44) group, older (45-54) subjects had significant OS, which may be related to duration of exposure.
Other Latest Articles
- Some Aspects Affecting the Molecular Mechanisms of Eukaryotic Adaptation under Global Warming
- Therapeutic Trials of Nigella sativa
- Identification of a Target Region for Specific Molecular Diagnosis of Human Papillomavirus Subtype 16
- Nectandra acutifolia (Ruiz & Pav.) Mez (Lauraceae) Reduces Oxidative Stress Induced with Rotenone in Drosophila melanogaster
- Tumor-Infiltrating Lymphocytes in Primary Tumor and Bone Marrow in Patients with Gastric Cancer and Overweight
Last modified: 2022-06-23 10:08:44