Sperm Donation in IUI and Preeclampsia’s Risk: Case of Reoccurrence in Patient with the Same Donor

Preeclampsia remains a major obstetrical problem, affecting 3-5% of pregnancies and can be up to 18% in some African countries. Epidemiological studies based on the immune theory showed the relationship between exposition to sperm and preeclampsia. Repeated exposition to seminal liquid would therefore be a protection against preeclampsia, as observed in women having frequent unprotected sex, or having had a previous normal pregnancy with the same partner. Other publications showed an increased risk of preeclampsia in patients who received sperm during an intrauterine insemination (IUI) or during an in vitro fertilization (IVF). We report a case of reoccurrence of severe preeclampsia in a mixed afro-caucasian couple having had a child delivered normally at term in the past. The couple later went for a sperm donation as a result of a chemotherapeutic treatment for Hodgkin Lymphoma which the man suffered from. The fact that the sperm was gotten from the same donor did not stop the reoccurrence. The first pregnancy gotten from sperm donation ended up into a medical termination of pregnancy (MTP) at 23 weeks 2 days of amenorrhea, and the second pregnancy issued from the same donor ended into a cesarean delivery at 28 weeks of a child with intrauterine growth retardation (IUGR).