Assessment of Heart Rate Variability and Heart Rate Turbulence Parameters in the Patients with Arterial Hypertension of the II Degree

Background: AH (Arterial hypertension) due to the extremely high incidence is the most important risk factor for development of myocardial infarctions, strokes and lethal outcomes. It is very important to identify a group of patients with increased risk of adverse outcomes to modify treatment and prevention. Significant assistance in resolving this problem is to provide a method of HM (Holter monitoring) which allows estimating the HRV (heart rate variability) and HRT (heart rate turbulence) parameters that are independent risk predictors of sudden cardiac death. The aim of our study was to assess HRV and HRT parameters in patients with AH of the II degree. Materials and methods: We have studied parameters of HRV and HRT in 214 patients with AH of the II-nd degree aged 35 to 70 (57.7 ± 7.6) years: 121 women (56.5%) and 93 men (43.5%). All patients underwent electrocardiography and echocardiography. Statistical analysis of the results has been made using the analytical package Statistics 10.0. Results: The parameters of HRV and HRT in patients with AH of the II degree were studied. Statistically significant correlations of the HRV parameters with the age of patients, average HR, circadian index, and EF (ejection fraction) were revealed. Statistically significant correlations of the HRT parameters with the LVMI (left ventricular mass index), EF, HR average were received. High level of the statistical significance of the interrelation of HRT parameters (TO and TS) has been revealed. Conclusions: The received results can be used during the selection of the group of patients with AH having high risk for unfavorable outcomes. Taking into account the features of the HRV and turbulence parameters and factors associated with them this will enable the individualization of the assessment of the risk in AH as much as possible and prescription of adequate treatment for each patient.