EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY OF ANNONA MURICATA L. EXTRACTS

Medicinal plants continue to play an important part in satisfying people's basic health care needs all around the world. Plant extracts are used to treat a variety of ailments. Annona muricata L, an essential medicinal plant used to treat cancer, malaria, neuralgia, arthritis, diarrhoea, dysentery, and other conditions, was chosen for testing its antioxidant capacity utilising in vitro methods such as DDPH, ABTS, and the Nitric oxide radical scavenging assay. The methanol extract of Annona muricata L had the best antioxidant activity, with suppression of DPPH and ABTS radicals of 85.70 percent (IC50=0.127 mg/mL) and 98.60 percent (0.130 mg/mL) respectively. The chloroform extract of Annona muricata L showed maximum of47.36% nitric oxide (NO) inhibition with IC50 being 0.856 mg/mL with the tested concentrations (100-500 µg). When compared to other extracts, the methanol extract of Annona muricata L was very efficient against free radical–mediated illnesses.