Phytochemicals in the Inhibition of COVID 19 A Systematic Review

Ayurvedic medicines has benefits as adjuvant or main stream therapy in the treatment of COVID 19. This study identifies and recommends the evidence based herbs to aid the development of successful herbal products against COVID 19 and their variants. Aims This review article aims to systematically review existing articles on drug research in Ayurveda from AYUSH Research portal Method A search in AYUSH Research portal was conducted to retrieve studies conducted from January 2020 to December 2021. Using Inclusion criteria, we selected both in silico and in vitro studies that described the role of phytocompounds in ameliorating COVID 19. Results and conclusion Majority of the articles have focused on phytochemicals from W.somnifera targeting main protease of SARS CoV 2. The study method in all the articles is molecular docking and molecular dynamics. The experimental evidence for the prediction is very rare. The mean molecular docking scores of phytochemicals is 5.9 Kcal mol which is like the control values. In conclusion, there is a need to explore phytochemicals from other plants with experimental evidence such that the studies can aid lead identification. Dr. Annapoorna S "Phytochemicals in the Inhibition of COVID-19: A Systematic Review" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-1 , December 2021, URL: https://www.ijtsrd.com/papers/ijtsrd48021.pdf Paper URL: https://www.ijtsrd.com/medicine/ayurvedic/48021/phytochemicals-in-the-inhibition-of-covid19-a-systematic-review/dr-annapoorna-s