A Review on Atopic Dermatitis Etiology, Clinical Features, Pathogenesis, Diagnosis, and Various Treatments
Journal: International Journal of Trend in Scientific Research and Development (Vol.6, No. 3)Publication Date: 2022-04-02
Authors : Jayaprakash U Preethi T C. J. Glady Gloria Grant;
Page : 1476-1487
Keywords : Atopic Dermatitis; Filaggrin; Flare-ups; Human monoclonal antibody;
Abstract
Atopic dermatitis is a recurrent, chronic inflammatory skin disease which affects children. Dermatitis is derived from the Greek words derma skin and itis inflammation . It affects 10 20 of adolescents and 1 3 percent of adults over their lifetime are caused by a complicated interaction between relevant genes, the environment of the host, pharmacological aberrations, and immunological variables. Two primary theories have been postulated. The first theory is that the adaptive immune system is out of balance, and the second is that the skin barrier is impaired. There is no specific test for Atopic dermatitis. Topical or systemic treatments are indicated depending on the severity of the Atopic dermatitis. It includes emmolients, corticosteroids, calcineurin inhibitors, phosphodiesterase 4 inhibitors, biological and wet wrap therapy. Once remission has been achieved, proactive maintenance therapy should be used to limit the number of flare ups. Jayaprakash U | Preethi T | C. J. Glady Gloria Grant "A Review on Atopic Dermatitis: Etiology, Clinical Features, Pathogenesis, Diagnosis, and Various Treatments" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-3 , April 2022, URL: https://www.ijtsrd.com/papers/ijtsrd49758.pdf Paper URL: https://www.ijtsrd.com/pharmacy/other/49758/a-review-on-atopic-dermatitis-etiology-clinical-features-pathogenesis-diagnosis-and-various-treatments/jayaprakash-u
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