Invitro Evaluation of Antibacterial Activity of Honey against Wound Pathogen

The medicinal importance of honey has been documented in the worlds oldest medical literatures, and since the ancient times, it has been known to possess antimicrobial property as well as wound healing activity. The healing property of honey is due to the fact that it offers antibacterial activity, maintains a moist wound condition, and its high viscosity helps to provide a protective barrier to prevent infection. Its immunomodulatory property is relevant to wound repair too. The antimicrobial activity in most honeys is due to the enzymatic production of hydrogen peroxide. However, another kind of honey, called non peroxide honey viz., manuka honey , displays significant antibacterial effects even when the hydrogen peroxide activity is blocked. Its mechanism may be related to the low pH level of honey and its high sugar content high osmolarity that is enough to hinder the growth of microbes. The medical grade honeys have potent in vitro bactericidal activity against antibiotic resistant bacteria causing several life threatening infections to humans. Thus, identification and characterization of the active principle s may provide valuable information on the quality and possible therapeutic potential of honeys against several health disorders of humans , and hence we discussed the medicinal property of honeys with emphasis on their antibacterial activities. J. Ishwarya | R. Ellammal "Invitro Evaluation of Antibacterial Activity of Honey against Wound Pathogen" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-4 , June 2022, URL: https://www.ijtsrd.com/papers/ijtsrd50210.pdf Paper URL: https://www.ijtsrd.com/biological-science/microbiology/50210/invitro-evaluation-of-antibacterial-activity-of-honey-against-wound-pathogen/j-ishwarya