EFFECT ON BODY WEIGHT AND FEED CONSUMPTION OF BISPHENOL - A INDUCED SUBACUTE TOXICITY IN RATS
Journal: Exploratory Animal and Medical Research (Vol.4, No. 2)Publication Date: 2014-12-31
Authors : S.S. Karnam; R.C. Ghosh; S. Mondal;
Page : 228-234
Keywords : Bisphenol-A; Body weight; Feed consumption; Wistar rat.;
Abstract
A subacute toxicity study of Bisphenol-A was conducted to investigate its toxic potential and as well as impact on mammals using wistar rat. The doses chosen were 50, 200 and 600 mg/kg body weight for group III, IV and V respectively and group II served as vehicle control and group I was negative control. Relative weights of different organs differed significantly (P < 0.05). Feed consumption and body weight were significantly (P < 0.05) reduced in the rats of group III, IV and V in dose dependant manner. It has toxic potential to induce anorexia.
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