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Chemical Analysis of Anti Covid Medications

Journal: International Journal of Trend in Scientific Research and Development (Vol.6, No. 5)

Publication Date:

Authors : ;

Page : 1658-1664

Keywords : virus; anti-COVID; antiviral; drugs; SARS-CoV-2; computational; chemistry;

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Abstract

At the end of 2019, a novel virus causing severe acute respiratory syndrome spread globally. There are currently no effective drugs targeting SARS CoV 2. In this study, based on the analysis of numerous references and selected methods of computational chemistry, the strategy of integrative structural modification of small molecules with antiviral activity into potential active complex molecules has been presented. Proposed molecules have been designed based on the structure of triterpene oleanolic acid and complemented by structures characteristic of selected anti COVID therapy assisted drugs. Their pharmaceutical molecular parameters and the preliminary bioactivity were calculated and predicted. The results of the above analyses show that among the designed complex substances there are potential antiviral agents directed mainly on SARS CoV 2. Dr. Ashutosh Tripathi "Chemical Analysis of Anti-Covid Medications" Published in International Journal of Trend in Scientific Research and Development (ijtsrd), ISSN: 2456-6470, Volume-6 | Issue-5 , August 2022, URL: https://www.ijtsrd.com/papers/ijtsrd51724.pdf Paper URL: https://www.ijtsrd.com/chemistry/other/51724/chemical-analysis-of-anticovid-medications/dr-ashutosh-tripathi

Last modified: 2022-09-06 20:19:46